Until Now
MedicineBiology

The first drug to slow Alzheimer's

Amyloid is cleared from the brain, and decline slows by about a quarter.

When
Known to
± 12 hours
Era
Contemporary, Holocene

Lecanemab was fully approved in the United States on 6 July 2023, the first treatment shown to change the course of Alzheimer's rather than its symptoms. The effect is modest and the drug carries a risk of brain swelling and bleeding requiring regular scans. After thirty years of failure it vindicated the amyloid hypothesis just enough to keep the argument going.

Sources

Just before

Just after